Natural history and prognostic factors for chronic hepatitis type B.
نویسندگان
چکیده
منابع مشابه
Natural history and prognostic factors for chronic hepatitis type B.
One hundred and five hepatitis B surface antigen (HBsAg) positive patients presenting with chronic persistent hepatitis (n = 46) or chronic active hepatitis without cirrhosis (n = 59) were followed longitudinally for one to 16 years (mean 5.5 years) and underwent follow up biopsy. During a mean histological follow up of 3.7 years, active cirrhosis developed in 21 (20%) patients one to 13 years ...
متن کاملEpidemiology, Risk Factors, and Natural History of Chronic Hepatitis C
• Approximately 3% of the world’s population is infected with the hepatitis C virus (HCV) with the highest prevalence rates noted in Africa and Asia. • In the United States, the incidence of HCV infection is declining secondary to effective blood donor screening adopted in the early 1990s and changing practices of intravenous drug users due to an increased awareness of HIV and hepatitis. • Hepa...
متن کاملThe natural history of chronic hepatitis B virus infection.
Under most circumstances, HBV is not cytopathic and it is the immune response of the host that determines the outcome of infection. The most complete immune response is associated with the most severe liver injury and the greatest likelihood of viral clearance, whereas an immature immune response leads to chronic hepatitis. The natural history of chronic hepatitis B is similar to that of acute ...
متن کاملThe natural history of chronic hepatitis B infection
Chronic hepatitis B infection is a global health problem that affects about 300 million people. Of these, 75% are Chinese. Most Chinese who become chronic carriers, contract the virus during the perinatal period. The natural history of these chronic hepatitis B carriers includes an initial immune tolerance phase, followed by immune clearance and an inactive hepatitis B non-replicative phase wit...
متن کاملPrognostic factors in severe exacerbation of chronic hepatitis B.
Forty-seven patients with severe hepatitis B exacerbation were compared with patients who had mild exacerbation (n=96) or no exacerbation (n=96). Seventeen patients (36.2%) died or underwent liver transplantation. Preexisting cirrhosis and a prothrombin time (PT) of >30 s were associated with adverse outcome in 60.9% and 87.5% of patients, respectively. The rate of adverse outcome increased to ...
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ژورنال
عنوان ژورنال: Gut
سال: 1991
ISSN: 0017-5749
DOI: 10.1136/gut.32.3.294